Overview of Next‐Generation Sequencing Technologies
نویسندگان
چکیده
منابع مشابه
Lecture 16: Sequencing Technologies
Introduction This lecture covered current and state-of-the-art methods in genome sequencing, and covered mostly biological topics and not algorithmic ones. Sequencing is the process of determining the complete order of nucleotides present in a DNA strand. This is a fundamental process for much of computational biology, as alignment, motif discovery, the Extended Haplotype Homozygocity test, and...
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The human genome sequence has profoundly altered our understanding of biology, human diversity, and disease. The path from the first draft sequence to our nascent era of personal genomes and genomic medicine has been made possible only because of the extraordinary advancements in DNA sequencing technologies over the past 10 years. Here, we discuss commonly used high-throughput sequencing platfo...
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High throughput sequencing technologies have become essential in studies on genomics, epigenomics, and transcriptomics. Although sequencing information has traditionally been elucidated using a low throughput technique called Sanger sequencing, high throughput sequencing technologies are capable of sequencing multiple DNA molecules in parallel, enabling hundreds of millions of DNA molecules to ...
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ژورنال
عنوان ژورنال: Current Protocols in Molecular Biology
سال: 2018
ISSN: 1934-3639,1934-3647
DOI: 10.1002/cpmb.59